Regenerative Medicine

Biomedical Engineering, Biological Sciences, and Animal Science

Internship

Central to preparing students for careers in regenerative medicine is a rigorous internship at a company or academic laboratory focused on Regenerative Medicine and/or Stem Cell Research. The Internship will occur over nine-months (Sep 1 - May 31) at one of our partner institutions. The Internship Project(s) will be designed to allow the students to progress from supervised to independent work, with the goal of collecting results of a publishable volume and quality. The Internship will culminate with a written report and oral presentation of the Internship Project, and an evaluation by the Intern’s Supervisor. Overall, the Internship will provide trainees the opportunity to master their laboratory skills, and develop their critical thinking, problem-solving, and communication skills.  

Industry Sites

CSL Behring

  • ex vivo gene modification of hematopoeitic stem cells for treating rare diseases, such as Sickle Cell Disease, and in vitro model systems to assess gene-modied cells
  • Intern Hosts: Cell Manufacturing & Process Development, Bioanalytics, and Gene Therapy Groups

Genentech

  • iPSC-derived models to evaluate cardiotoxicity and neurotoxicity of investigational compounds probe mechanisms of toxicity
  • Intern Hosts: Investigative Toxicology Group in the department of Safety Assessment in Research and Early Development 

Kite Pharma

  • Process optimization or characterization of T cell activation, T cell expansion in static and perfusion bioreactors, and formulation optimization for low doses
  • Intern Hosts: Process Development Group 

Rubedo Life Sciences

  • Pharmacological approach to induce apoptosis in senescent cells to improve stem cell function in multiple tissue to mitigate effects of chemotherapy toxicity 
  • Intern Hosts: Preclinical Research

T-Cure Bioscience

  • Identification of T-Cell Receptors (TCR) that recognize epithelial tumor antigens and preclinical characterization of leukocytes transduced with promising TCRs
  • Intern Hosts: Research & Development

ThermoFisher Scientific

  • Developing tools for iPSC generation and differentiation, and for manufacturing/quality control of clinical therapies
  • Intern Hosts: Cell Biology Group

ViaCyte

  • Combination product comprising stem cell-derived beta cells in an immunoisolation device to treat type I diabetes
  • Intern Hosts: Product Engineering Group and Cell Engineering Group

Academic Sites

The Salk Institute

University of California, San Diego

Stem Cell Techniques Course

Microscopic cellPrior to embarking on the 9-month internship, students will complete a 2-week intensive Pluripotent Cell Techniques Course at the ThermoFisher Scientific. During this experience, students will be trained in human pluripotenet stem cell culture, embryoid body development, directed cellular differentiation, and other hands-on skills for working with and evaluating stem cells.

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